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EMU Journal of Pharmaceutical Sciences
Vol. 7 No. 3 (2024)MESSAGE FROM EDITOR IN CHIEF
Dear Colleagues,
We are at the end of 2024. I would like to wish you a happy new year!
As editorial board of EMU Journal of Pharmaceutical Sciences, we also have the pleasure to introduce you the final (3rd) issue of Volume 7, 2024.
Within the content of this issue, there are again quite interesting articles waiting for you to be explored. Physics and pharmacy appear to be different scientific areas. In the review part, the employment of physics in selected pharmaceutical areas has been discussed. The biological evaluation of Corchorus olitorius L. (Molokhia) leaves, and folk medicine/morphological characteristics of Eucalyptus gomphocephala and Eucalyptus camaldulensis in Northern Cyprus have been stated in other research articles. The preparation and evaluation of water-soluble curcumin-cyclodextrin-PVP inclusion complexes generated interesting work. Finally, microwave-assisted synthesis and anticancer activity study for a spiro compound have also been introduced to readers. We are grateful to all authors of this issue.
In the soon period, we are looking forward to your scientific contributions that will be published in EMU Journal of Pharmaceutical Sciences Volume 8 issues of 2025.
Best wishes,Prof. Dr. H. Ozan Gülcan
Dean of Faculty of Pharmacy
Editor in Chief
Eastern Mediterranean University
Faculty of Pharmacy
Famagusta, TRNC, via Mersin 10 TurkiyeCONTENTS
Research articles
Synthesis and Anti-Cancer Activity of New Spiro[5.5]undecane Compound by Efficient Microwave Reaction
Vildan Burgaz, Imge Kunter
Microscopic Evaluation and Qualitative Phytochemical Screening of Corchorus olitorius L. (Molokhia) Leaves
Beste Atli, Nesrin Oztinen, Ezgi Ak-Sakalli, Betul Topalkara, Muberra Kosar
Assessment of the Usage in Folk Medicine and Morphological Characteristics of Eucalyptus gomphocephala and Eucalyptus camaldulensis in Northern Cyprus
Gizem Kinel, Tugba Ercetin
Preparation and Evaluation of Water-Soluble Curcumin-Cyclodextrin-PVP Inclusion Complexes
Nardin Sedghizadeh, Aysan Davatgaran Taghipoor, Ertugrul Ozbil, Leyla Beba Pozharani
Reviews
Review Article: Integral Role of Physics in Advancing Pharmacy Education and Research
İzzet Sakallı
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EMU Journal of Pharmaceutical Sciences
Vol. 7 No. 2 (2024)MESSAGE FROM EDITOR IN CHIEF
Dear Colleagues,
It is a pleasure to introduce the 2nd issue of EMU Journal of Pharmaceutical Sciences Volume 7, 2024. I would like to congratulate all participants, editorial board, and the journal secretarial for the hard work achieved out.
As a member of ‘DergiPark’ Akademik, an establishment under the Scientific and Technological Research Council of Türkiye (TÜBİTAK), EMU Journal of Pharmaceutical Sciences continues its journey on the welcoming, pure reviewing, and publication of scientific studies in diverse fields related to pharmaceutical sciences. The journal will continue to serve, promote, and disseminate scientific research information globally while giving scientists and researchers a higher platform to share their scientific word in the whole world. It is important to remind that the journal is free of submission or acceptance fee.
MESSAGE FROM EDITOR IN CHIEF
Dear Colleagues,
It is a pleasure to introduce the 2nd issue of EMU Journal of Pharmaceutical Sciences Volume 7, 2024. I would like to congratulate all participants, editorial board, and the journal secretarial for the hard work achieved out.
As a member of ‘DergiPark’ Akademik, an establishment under the Scientific and Technological Research Council of Türkiye (TÜBİTAK), EMU Journal of Pharmaceutical Sciences continues its journey on the welcoming, pure reviewing, and publication of scientific studies in diverse fields related to pharmaceutical sciences. The journal will continue to serve, promote, and disseminate scientific research information globally while giving scientists and researchers a higher platform to share their scientific word in the whole world. It is important to remind that the journal is free of submission or acceptance fee.
In the soon period, we are planning to launch the 3rd issue of the year.
Looking forward to your scientific contributions,
Best wishes,Prof. Dr. H. Ozan Gülcan
Dean of Faculty of Pharmacy
Editor in Chief
Eastern Mediterranean University
Faculty of Pharmacy
Famagusta, TRNC, via Mersin 10 TurkiyeCONTENTS
Research articles
Comparison of In Vitro Ibuprofen Release Rates from HPMC and Carbopol 934® Gels
Emine Dilek Ozyilmaz, Acelya Mavideniz, Zahra Nobavar
Determining the Assay of New Formulation Low Dosage Naltrexone HCl Capsules with a RP-HPLC Method
Vildan Burgaz
Antibacterial Activity of Naltrexone and Its Combination with Ciprofloxacin Against Gram negative and Gram positive Bacteria
Ertugrul Ozbil, Sultan Ogmen, Mehmet Ilktac
Enhanced Antibacterial Efficacy of Cymbopogon winterianus Jowitt in Combination with Carvacrol
Ezgi Ak-Sakalli, Mehmet Ilktac, Beste Atli, Nesrin Oztinen, Muberra Kosar, Fatih Demirci
Reviews
Chronotoxicity Studies in Pharmaceutical Science: A Comprehensive Review
Ulfet Gudul, Hananeh Kordbacheh, Sonia Sanajou, Gonul Sahin
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EMU Journal of Pharmaceutical Sciences
Vol. 7 No. 1 (2024)EMU Journal of Pharmaceutical Sciences Vol. 7 No. 1 ( July 2024 )EMU Journal of Pharmaceutical Sciences (EMUJPharmSci), which is an open access peer-reviewed journal, publishes original research and review articles. The contributions to the journal must be written in English. The journal has been published regularly thrice a year since 2018.
The journal covers the research on all aspects of Pharmacy presented as original articles, short reports and reviews. In our journal, publications are the recent studies on the basis of Pharmaceutical Sciences including, Pharmaceutical Toxicology, Pharmaceutical Chemistry, Pharmacognosy, Pharmaceutical Botany, Pharmaceutical Technology, Pharmaceutical Biotechnology, Pharmaceutical Microbiology, Pharmacology and also other topics related with the pharmaceutical area.
CONTENTS
Research articles
Development of Zinc-loaded Hydrogel Infused with Aloe Barbadensis Mucilage for Wound Healing
Ibilola Mary Cardoso-daodu, Emmanuel Chibuike Agbarakwe, Margaret Okonawan Ilomuanya, Chukwuemeka Paul Azubuike, Boladale Olanrewaju Silva
Screening Cholinesterase Inhibitory Potential of Selected Amines
Acelya Mavideniz, Tugba Ercetin, Aybike Yektaoglu, Zahra Nobavar, Jale Yuzugulen, Emine Dilek Ozyilmaz, Hayrettin Ozan Gulcan
Antibacterial Potency of Ibuprofen and Its Interaction with Ciprofloxacin against Gram Positive and Gram Negative Bacteria
Ertugrul Ozbil, Sultan Ogmen, Acelya Mavideniz, Mehmet Ilktac
In vitro Antibacterial Activity of Naproxen and its Combination with Ciprofloxacin
Sultan Ogmen, Ertugrul Ozbil, Acelya Mavideniz, Mehmet Ilktac
Review
Antimicrobial Activity of Pimpinella – an Overview
Mehmet Ilktac, Zeynep Pelin Kutlug, Yanki Celebi, Gülden Celik
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EMU Journal of Pharmaceutical Sciences
Vol. 6 No. 1 (2023)EMU Journal of Pharmaceutical Sciences (EMUJPharmSci), which is an open access peer-reviewed journal, publishes original research and review articles. The contributions to the journal must be written in English. The journal has been published regularly thrice a year since 2018.
The journal covers the research on all aspects of Pharmacy presented as original articles, short reports and reviews. In our journal, publications are the recent studies on the basis of Pharmaceutical Sciences including, Pharmaceutical Toxicology, Pharmaceutical Chemistry, Pharmacognosy, Pharmaceutical Botany, Pharmaceutical Technology, Pharmaceutical Biotechnology, Pharmaceutical Microbiology, Pharmacology and also other topics related with the pharmaceutical area.
CONTENTS
Research articles
Evaluation of Microbiological Cleanliness of Machines/Equipment through Rinse Technique Using Statistical Process Control …………………………………………................................................................………1
Mostafa Essam Eissa, Engy Refaat Rashed
Antimicrobial Activity Studies of 3-Substituted Indole-2-one and -thione derivatives and Molecular Docking and ADME Evaluations…………………………...................................……………………….13
Derya Doganay, Sevval Maral Ozcan Aykol, Ahmet Mesut Senturk, Sureyya Olgen
Synthesis and cholinesterase inhibitory potential of 2-phenoxy-N-substituted-acetamide derivatives…………………………………………………………………………………..............................................…….27
Kiana Harati, Seyedeh Mahta Kiaei, Tina Mahdipour Amjad, Zahra Nobavar, Karar Tawfeeq Shukur, Acelya Mavideniz, Tugba Ercetin, Hayrettin Ozan Gulcan
Formulation development and evaluation of controlled release matrix tablets of glibenclamide…………………............................................…………………………………………………………….…...34
Biji Palatty Anthony, Rajendran Praveen Raj, Daisy Punnackal Augustine
Reviews
Common Treatment Formulation for Non-Scaring (Androgenetic) Alopecia: Mini Review…………................................................……………………………………………………………………………..….56
Jannat WH Al-Jubouri, Leyla B Pozharani, Metin Celik
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EMU Journal of Pharmaceutical Sciences
Vol. 5 No. 1 (2022)EMU Journal of Pharmaceutical Sciences (EMUJPharmSci), which is an open access peer-reviewed journal, publishes original research and review articles. The contributions to the journal must be written in English. The journal has been published regularly thrice a year since 2018.
The journal covers the research on all aspects of Pharmacy presented as original articles, short reports and reviews. In our journal, publications are the recent studies on the basis of Pharmaceutical Sciences including, Pharmaceutical Toxicology, Pharmaceutical Chemistry, Pharmacognosy, Pharmaceutical Botany, Pharmaceutical Technology, Pharmaceutical Biotechnology, Pharmaceutical Microbiology, Pharmacology and also other topics related with the pharmaceutical area.
CONTENTS
Research articlesDevelopment and validation of new RP-HPLC Method for estimation of pramipexole dihydrochloride in bulk and pharmaceutical formulation.
Moein Amel, Leyla Beba Pozharani, E. Vildan Burgaz, Omer TurkmenPollen morphology of some taxa in the family Lamiaceae (Labiatae) from Turkey.
Zeynel Ozaltan, Mine KocyigitRichness of wild flowering plants and ferns in Northern Cyprus.
F. Neriman Ozhatay, Ertugrul Ozbil, Sultan OgmenInfluence of carnauba wax on the release profile of ibuprofen implants.
Airemwen Collins Ovenseri, Isesele Ejededawe Jude, Obarisiagbon Aiwaguore Johnbull, Emmanuel Mshelia Halilu, Uhumwangho MUReviews
Tea Tree (Melaleuca alternifolia (Maiden & Betche) Cheel) Oil: An important medicinal essential oil.
Gita Parviz, Muberra Kosar, Fatih Demirci -
EMU Journal of Pharmaceutical Sciences
Vol. 4 No. 1 (2021)EMU Journal of Pharmaceutical Sciences (EMU JPharmSci) is a peer reviewed, open access journal that is dedicated to any discipline under the category of pharmaceutical sciences. It publishes research articles, short communications, and reviews under the pharmacy discipline. These include pharmaceutical chemistry, biochemistry, pharmacognosy, pharmaceutical botany, microbiology, toxicology, the history of pharmacy and areas such as phytotherapy, ethnobotany, sports pharmacy, which have gained importance in recent years, are also included within the scope of the journal. The journal is aimed to be published for three times a year and the first volume is published on November 2018. The publication language is English. The aims of the journal are to contribute to the scientific development and advancement of researchers within the field of pharmacy and to allow the exchange of information among readers.
CONTENTS
Research articles
Phytoequivalency of Ginkgo biloba products: Pharmacopoeial method.
Haleh Piri, Beste Atli, Nesrin Oztinen, Ezgi Ak-Sakalli, Muberra Kosar
Honey plants of Tepebaşı (Diorios) in North Cyprus.
Bilge Turkseven, F. Neriman Ozhatay
Antiradical activities and phenolic compositions of Rosa canina L. from Iran and Turkey.
Deniz Jafari Javid, Ezgi Ak-Sakalli, Nesrin Oztinen, Beste Atli, Muberra Kosar
Reviews
Short Review: A new promising technology to ensure drug safety.
Emine Dilek Ozyilmaz
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EMU Journal of Pharmaceutical Sciences
Vol. 3 No. 3 (2020)EMU Journal of Pharmaceutical Sciences (EMU JPharmSci) is a peer reviewed, open access journal that is dedicated to any discipline under the category of pharmaceutical sciences. It publishes research articles, short communications, and reviews under the pharmacy discipline. These include pharmaceutical chemistry, biochemistry, pharmacognosy, pharmaceutical botany, microbiology, toxicology, the history of pharmacy and areas such as phytotherapy, ethnobotany, sports pharmacy, which have gained importance in recent years, are also included within the scope of the journal. The journal is aimed to be published for three times a year and the first volume is published on November 2018. The publication language is English. The aims of the journal are to contribute to the scientific development and advancement of researchers within the field of pharmacy and to allow the exchange of information among readers.
CONTENTS
Research articles
Direct SPME/GC-MS analyzes of small citrus fruits cultivated in Turkey
Hale Gamze Agalar, Burak Temiz, Betul Demirci, K. Husnu Can BaserThe effects of some organic solvents on the modified Ellman procedure for the assay of cholinesterases
Tugba Ercetin, Acelya Mavideniz, Karar Tawfeeq Shukur, Ali Khosravi, Bahamehr Riazi, Fatemeh
Salamati, Houra Shahinfar, Mohammad Najjaran, Muzahem Imad Ahmed, Nasim Maher, Negar
Khajeh, Nezhla Kazemi Davdar, Salva Shahinfar, Hayrettin Ozan GulcanInvestigation of CRISPR anti-phage systems of Lactobacillus plantarum from pickled olives
A. Esra Eren, Ihsan Yasa, Nazenin EftekhariMorphological and leaf anatomical structure of Pimpinella cypria Boiss
Sevdenur Muti, F. Neriman OzhatayThe ethnobotany, systematics and morphological studies of the genus Ornithogalum that naturally grows in Kahramanmaras province of Southern Turkey
Serpil Demirci Kayiran, F. Neriman OzhatayFormulation and chracterization of meloxicam loaded niosome-based hydrogel formulations for topical applications
Leyla Beba Pozharani, Sheida Zarifi AzarReviews
Myrtle (Myrtus communis L.) and potential health effects
Seliz Bagcilar, Ceren Gezer -
EMU Journal of Pharmaceutical Sciences
Vol. 3 No. 2 (2020)EMU Journal of Pharmaceutical Sciences (EMU JPharmSci) is a peer reviewed, open access journal that is dedicated to any discipline under the category of pharmaceutical sciences. It publishes research articles, short communications, and reviews under the pharmacy discipline. These include pharmaceutical chemistry, biochemistry, pharmacognosy, pharmaceutical botany, microbiology, toxicology, the history of pharmacy and areas such as phytotherapy, ethnobotany, sports pharmacy, which have gained importance in recent years, are also included within the scope of the journal. The journal is aimed to be published for three times a year and the first volume is published on November 2018. The publication language is English. The aims of the journal are to contribute to the scientific development and advancement of researchers within the field of pharmacy and to allow the exchange of information among readers.
CONTENTS
Research articles
Comparison of the pharmaceutical properties of paracetamol tablets belonging to different companies in the Northern Cyprus pharmaceutical market
Emine Dilek Ozyilmaz, Tansel Comoglu, Roya NourmohammadiMicrowave assisted synthesis of ethyl 2,2-bis(4-fluorophenyl)-4-oxo-3,4-dihydro-2H-furo[3,2-c]chromene-3-carboxylate via manganese(III) acetate mediated radical cyclization reaction
Negar Khezri, E. Vildan BurgazA study on life expectancy in Turkey
Canan GulcanThe genus Persicaria (Polygonaceae) in Turkey with a new taxon record
Mustafa Keskin, Zeki SeverogluLamiaceae in Turkey: Additional taxa 2000-2019
F. Neriman Ozhatay, Sukran Kultur, Bahar GurdalReviews
Urolithins and their antimicrobial activity: A short review
Omar Mohamed Aboelftouh Ammar, Mehmet Ilktac, Hayrettin Ozan GulcanEvaluation of the recommended treatment and preventive measures of COVID-19
Hananeh Kordbacheh, Ahmet Aydin, Sonia Sanajou, Gonul Sahin -
EMU Journal of Pharmaceutical Sciences
Vol. 3 No. 1 (2020)EMU Journal of Pharmaceutical Sciences (EMU JPharmSci) is a peer reviewed, open access journal that is dedicated to any discipline under the category of pharmaceutical sciences. It publishes research articles, short communications, and reviews under the pharmacy discipline. These include pharmaceutical chemistry, biochemistry, pharmacognosy, pharmaceutical botany, microbiology, toxicology, the history of pharmacy and areas such as phytotherapy, ethnobotany, sports pharmacy, which have gained importance in recent years, are also included within the scope of the journal. The journal is aimed to be published for three times a year and the first volume is published on November 2018. The publication language is English. The aims of the journal are to contribute to the scientific development and advancement of researchers within the field of pharmacy and to allow the exchange of information among readers.
CONTENTS
Research articles
Separation/preconcentration of antimony(III) by nickel/nickel boride nanoparticles prior to hydride generation atomic absorption spectrometric determination
Miray Kavas, Nur Aksuner, Raif Ilktac, Emur HendenAnatomical studies of Dracocephalum moldavica L., Ocimum basilicum L. and Agastache rugose (Fisch. & C.A.MEY) Kuntze (Lamiaceae) used for cardiovascular diseases in traditional Uyghur medicine
Nuerbiye Aobuliaikemu, Mine KocyigitInvestigation of cholinesterase inhibitory potential of chlorinated phenols
Bahareh Noshadi, Tugba Ercetin, Acelya Mavideniz, Hayrettin Ozan GulcanDevelopment of effervescent tablet formulation which contain ferrous salt and ascorbic acid combination
Hasip Cem Ozyurt, Reza MehradStudy of in vitro immunomodulatory effect and quantitative evaluation of main phytoconstituents in Indian Drosera species
Raju Asirvathama, Aparna Ann Mathew, Salwa Abdul SalamReview
A review of oxidants and antioxidants in biological systems
Imge Kunter, Niloufar Zabib, Muberra Kosar -
EMU Journal of Pharmaceutical Sciences
Vol. 2 No. 2 (2019)EMU Journal of Pharmaceutical Sciences (EMU JPharmSci) is a peer reviewed, open access journal that is dedicated to any discipline under the category of pharmaceutical sciences. It publishes research articles, short communications, and reviews under the pharmacy discipline. These include pharmaceutical chemistry, biochemistry, pharmacognosy, pharmaceutical botany, microbiology, toxicology, the history of pharmacy and areas such as phytotherapy, ethnobotany, sports pharmacy, which have gained importance in recent years, are also included within the scope of the journal. The journal is aimed to be published for three times a year and the first volume is published on November 2018. The publication language is English. The aims of the journal are to contribute to the scientific development and advancement of researchers within the field of pharmacy and to allow the exchange of information among readers.
CONTENTS
Research articles
Oleuropein amounts of olive leaves from different regions of Northern Cyprus
Hadeel Homssi, Muberra KosarForced degradation studies of new formulation containing naltrexone
Golnaz Yaghoubnezhadzanganeh, E. Vildan BurgazHealthy life-style patterns of pharmacists in Turkey
Hilal Ilbars, Secil OzkanPlant biodiversity and unique yew stands of Istranca (Yıldız) mountains in European Turkey
Mehtap Oztekin, Neriman OzhatayReview
The metabolites of ellagitannin metabolism urolithins display various biological activities
Jale Yuzugulen, Bahareh Noshadi, Karar Shukur, Mustafa Fethi Sahin, Hayrettin Ozan Gulcan -
EMU Journal of Pharmaceutical Sciences
Vol. 2 No. 1 (2019)EMU Journal of Pharmaceutical Sciences (EMU JPharmSci) is a peer reviewed, open access journal that is dedicated to any discipline under the category of pharmaceutical sciences. It publishes research articles, short communications, and reviews under the pharmacy discipline. These include pharmaceutical chemistry, biochemistry, pharmacognosy, pharmaceutical botany, microbiology, toxicology, the history of pharmacy and areas such as phytotherapy, ethnobotany, sports pharmacy, which have gained importance in recent years, are also included within the scope of the journal. The journal is aimed to be published for three times a year and the first volume is published on November 2018. The publication language is English. The aims of the journal are to contribute to the scientific development and advancement of researchers within the field of pharmacy and to allow the exchange of information among readers.
CONTENTS
Research articles
Investigation of Streptococcus pyogenes carriage among pharmacy students in North Cyprus
Sahar Haddad, Mehmet Ilktac, Sultan Ogmen, Gulden CelikScreening the cholinesterase inhibitory potential of some (1E, 4E)-1.5-diphenylpenta-1.4-dien-3-one derivatives
Acelya Mavideniz, Amirhossein Fallah, Foroogh Koshravi, Farimah Ahdno, Mehmet Arter, Tugba
Ercetin, Mustafa Fethi Sahin, Hayrettin Ozan GulcanOuter and inner morphological characteristics of Saturea and Thymbra taxa exported as Oregano from Turkey II
Narin Sadıkoglu, Neriman OzhatayAdsorption of iron, lead, paracetamol, imipramine on natural polymers
Gonul Sahin, Sonia Sanajou, Reihaneh Behnoush, Ehsan BahramzadeReview
Analgesic nephropathy
Gonul Sahin, Sonia Sanajou, Hananeh Kordbacheh -
EMU Journal of Pharmaceutical Sciences
Vol. 1 (2018)EMU Journal of Pharmaceutical Sciences, (EMU JPharmSci) is a peer reviewed open access journal that is dedicated to any discipline under the category of pharmaceutical sciences. It publishes the following articles: Research articles, Short communications, and Reviews in pharmaceutical, chemical, botanical, and microbiological research areas are all aimed to be presented within the scope of the journal.The journal is aimed to be published for three times a year and the first volume is published on November 2018. The publication language is English. The aims of the journal are to contribute to the scientific development and advancement of researchers within the field of Pharmacy and to allow the exchange of information among readers.
